Location: Downtown Boston

Pay Range: $60-$65/hr

Term: 6 months

Job Summary

We are seeking a highly motivated scientist to join our dynamic drug discovery biology team. This candidate will serve a critical role in establishing and running cell-based assays to inform target biology, in addition to supporting translational biology efforts. This position is ideal for a talented, highly motivated and results driven individual who will thrive in a fast-paced, innovative, start-up environment.

Key Responsibilities

Executing experiments to inform target biology using a variety of approaches, including cell line engineering, analysis of signaling pathways, and characterization of cell proliferation and death mechanism(s).
Executing high throughput cell-based assays.
Conducting mechanism of action studies on small molecule inhibitors (e.g. PD readouts by Western Blot)
Genetic manipulation of cells utilizing knockdown or knockout and over-expression of proteins for target validation.
Maintain high-quality, detailed experimental records within the ELN
Use organizational and communication skills to effectively collaborate with colleagues across pharmacology and biology

Professional Experience/Qualifications

BS in Biology or a related field, with oncology experience preferred but not required.
Relevant laboratory experience in industry or academia (e.g. summer internship)
Experience with cell culture, assay implementation, and data processing with excellent scientific rigor
Broad experience optimizing, running, and analyzing standard cellular assays (CTGlo, BrdU, HTRF, AlphaLISA)
Experience using the following software preferred but not required: SnapGene, GraphPad Prism, Spotfire/Certara D360, Scinamic
A highly engaged, self-starter who is creative, innovative, organized, communicative and possesses both a collaborative and goal/results-orientated style.
Proficiency analyzing data with excel, prism and experience using an ELN system
Desire to work in a fast-paced, multi-tasking team environment, while employing tact, patience, diplomacy and a collaborative spirit.

Jobs

Contract Scientist I, Biology

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