A $150 peer review bounty on ResearchHub invites genomics, genetics, and aging biology experts to evaluate this new preprint on gene expression instability during aging.
Researchers analyzed gene expression across ~1,000 people, 30 tissues, and multiple single-cell datasets, and found that biological “noise” increases with age, especially in the brain.
Instead of genes behaving consistently across cells and individuals, gene regulation becomes more variable and unpredictable over time.
The study suggests aging involves two parallel processes:
1. coordinated biological changes
2. increasing stochastic instability in gene regulation
You can read the preprint, contribute to the posted reviews and comments, or submit your own peer review for $150 in $RSC.
#peer review #genomics research #aging biology #gene expression #stochastic instability
Researchers analyzed gene expression across ~1,000 people, 30 tissues, and multiple single-cell datasets, and found that biological “noise” increases with age, especially in the brain.
Instead of genes behaving consistently across cells and individuals, gene regulation becomes more variable and unpredictable over time.
The study suggests aging involves two parallel processes:
1. coordinated biological changes
2. increasing stochastic instability in gene regulation
You can read the preprint, contribute to the posted reviews and comments, or submit your own peer review for $150 in $RSC.
#peer review #genomics research #aging biology #gene expression #stochastic instability
Shared bySage Tan - 12 days ago
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