Senior Scientist I, High Throughput Assays

Location of role Abingdon, UK

Department Protein Engineering

Key Responsibilities We are seeking a highly motivated senior scientist who will have key responsibilities for developing and implementing high throughput, automated biologic assay capabilities for the discovery of transformative immunotherapies. In addition to identifying and building innovative and state state-of-the-art high-throughput biochemical and cell assays to identify lead panels of potential candidate T cell-engager therapeutics, the role will involve liaising with drug discovery and automation scientists to establish new and improved technologies that streamline the discovery process.

Key Responsibilities:

• Independently identify, design, develop, and validate state of the art cell assays for assessment of target binding and functional properties of T cell engager molecules.
• Work alongside automation experts to build and implement high-throughput biochemical and cell binding assay capabilities.
• Analyse, interpret and effectively communicate experimental results, recommendations and plans to project teams.
• Maintain a good understanding of state-of-the-art and emerging biologics drug formats and the assays used for characterisation.
• Contribute to identifying, evaluating, building, and applying innovative biochemical and cell assays to streamline the drug discovery processes.
• Troubleshoot and identify resourceful, relevant solutions for complex scientific challenges.
• Contribute to internal and external collaborations.
• Provide technical training to team members where required
• Follow Good Laboratory Practice and adhere to Immunocore health and safety policies.
  
  

Supervisory Responsibility (If applicable):

• May oversee and manage the activities of lower-level personnel.
  
  

Education, Experience and Knowledge:

Essential Qualifications:

• Normally requires a PhD in a scientific discipline and a minimum of 2-5 years related experience; may include post-doctoral experience.
• Or MSc degree or BSc degree with extensive role-specific equivalent research or industrial experience.
  
  

Essential Experience, Knowledge & Abilities

• Experienced in developing, running and troubleshooting high-throughput biochemical and biologics assays
• Experienced in development of HTRF, DELFIA, Mirrorball and flow assays
• Experienced in use of automation e.g. liquid handlers
• Experienced in use of functional cell assays for biologics
• Track record of solving scientific problems creatively
• Track record of collaborating and contributing as a matrix project team member
• Effective communication of scientific concepts and findings
  
  

Preferred Experience, Knowledge & Abilities:

• Experience in scripting and troubleshooting of automation systems
• Experience in biologics drug discovery
• Track record of evaluating innovative solutions to improve processes
  
  

Other:

• Attention to detail and quality
• Strong organisation skills with ability to plan, prioritise and coordinate work with others
• Strong team player with ability to actively listen and work productively with other team members in a matrix environment
• Ability to communicate clearly to relevant audiences
• Demonstrates innovative thinking
  
  

About the Company Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.

Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.

At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients’ lives, advancing medicine, and supporting one another in these pursuits.

Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.